Autoimmunity Risk Calculator

Turn symptoms, history, habits, and labs into insight. Adjust inputs, compare scenarios, and export results. Use it for education, not diagnosis or treatment alone.

Calculator inputs
Fill what you know. Optional labs are welcome.
Tip: Leave BMI blank to calculate it.
Used as a population-level risk proxy.
Autoimmune diseases are more common in females.
Genetic predisposition can raise baseline risk.
Smoking is linked to higher inflammation and risk.
Optional: for BMI calculation.
Optional: for BMI calculation.
Leave blank to compute from height/weight.
Optional lab commonly linked to immune balance.
Higher chronic stress can affect immune signaling.
Sleep supports immune regulation and recovery.
Frequent infections may reflect immune stressors.
Repeated courses may affect microbiome balance.
Digestive symptoms may correlate with inflammation.
Symptoms can have many causes; this tool does not diagnose disease.
Reset
Optional lab values
If you don’t have these, you can leave them blank.
Antinuclear antibodies may indicate immune activity.
C-reactive protein rises with inflammation.
Erythrocyte sedimentation rate reflects inflammation.
Common thyroid autoantibody marker.
Lab interpretation depends on context, symptoms, and reference ranges. Always confirm results with a qualified clinician.
Formula used

This calculator uses a weighted point index. Each factor is assigned points based on typical associations reported in population studies (for example, family history, smoking, inflammation markers), then summed into a raw score.

  • Raw score = sum of points from each factor group
  • Risk % = min(100, (Raw score / 129) × 100)
  • Risk level is categorized by thresholds: Low < 25, Moderate 25–49.9, High 50–74.9, Very High ≥ 75

The model is educational and simplified. It does not replace clinical evaluation, diagnostic criteria, or individualized risk assessment.

How to use this calculator
  1. Enter your age, sex at birth, and family history.
  2. Add lifestyle and health factors like smoking, sleep, and stress.
  3. Optionally include lab values for a more detailed estimate.
  4. Press Calculate Risk to view the score above this form.
  5. Use download buttons to export results as CSV or PDF.
If you select several symptoms and have high inflammation markers, consider professional advice. Seek urgent care for severe breathing issues, chest pain, or neurological symptoms.
Example data table
Profile Key inputs Expected output
Example A Age 25, female, no family history, never smoker, BMI 22, sleep 7.5, stress 3, few infections Low risk range; lifestyle supports immune balance
Example B Age 42, female, one first-degree history, former smoker, BMI 31, sleep 6, stress 7, frequent gut symptoms Moderate to high range; review sleep and inflammation drivers
Example C Age 55, female, multiple first-degree history, current smoker, BMI 36, sleep 5, stress 9, ANA positive, CRP 12 High to very high range; discuss evaluation with a clinician

These examples are illustrative and do not represent medical advice.

What the score represents

This calculator produces a risk index, not a diagnosis. Each input adds points based on population associations with autoimmune activity. Points are summed into a raw total, then converted to a percentage using the model maximum of 129 points. The result is grouped into four bands: Low under 25%, Moderate 25–49.9%, High 50–74.9%, and Very High at 75% or more. Use the score to compare scenarios.

Inputs that carry the most weight

Family history and antibody markers contribute because inherited susceptibility and immune signaling can shift baseline risk. Lifestyle factors still matter: current smoking, short sleep, and high stress add points, while normal sleep and non‑smoking reduce the total. Body mass index is weighted to reflect inflammatory burden at higher ranges, and vitamin D values below 20 ng/mL increase points. The symptoms checklist adds up to 12 points when persistent symptoms are selected.

How optional labs refine estimates

Optional labs improve specificity by separating “unknown” from measured inflammation or autoantibodies. A positive ANA adds 12 points, while borderline adds 6, reflecting an increase. CRP above 10 mg/L and ESR above 40 mm/hr add more than mild elevations. TPO antibodies above 35 IU/mL raise points, which can be relevant to thyroid autoimmunity patterns. If you leave labs blank, the calculator still works, but the completeness indicator will be lower.

Interpreting the breakdown table

The breakdown table lists every factor and its point contribution, letting you see what is driving the percentage. Focus on modifiable items first: smoking status, stress score, sleep duration, BMI, infection frequency, and antibiotic exposure. When BMI is not provided, it is calculated from height and weight using BMI = kg / m² and shown as “calculated” to keep the record. Re-run the form after adjusting one variable to see its effect.

Using results for healthier planning

Use the output as a structured conversation starter. If your score is High or Very High and you also report persistent symptoms, consider discussing screening and follow‑up with a clinician. For Moderate scores, prioritize sleep quality, stress reduction, and smoking cessation, then recheck after consistent habits for several weeks. Keep a log of infections and medications because trends matter. Download CSV for tracking, and use the PDF summary when sharing results over time.

FAQs

Is this a medical diagnosis tool?

No. It is an educational estimator that combines risk-related factors into a single index. Autoimmune conditions require clinical history, exams, and validated diagnostic criteria interpreted by qualified professionals.

Which inputs influence the score the most?

Family history and optional antibody or inflammation markers can add larger point blocks. Lifestyle drivers such as smoking, sleep, stress, BMI, and symptom burden also shift the total and are often the most modifiable.

What if I don’t know my lab values?

Leave the optional lab fields blank or set ANA to Unknown. The calculator will still generate a score, and the completeness indicator will show that fewer measured markers were used.

How is BMI handled if I leave it blank?

If you enter height and weight, BMI is calculated as weight in kilograms divided by height in meters squared. If you provide BMI directly, that value overrides the calculated result.

Can I track changes over time?

Yes. Run the calculator periodically with updated inputs and download the CSV after each run. Keeping consistent measurement habits helps you see whether modifiable factors are trending in a healthier direction.

When should I seek professional evaluation?

If you have persistent symptoms, rapidly worsening issues, or a High/Very High score paired with abnormal labs, discuss the results with a clinician. Seek urgent care for severe chest pain, breathing trouble, or neurological symptoms.

Related Calculators

ELISA Result CalculatorLymphocyte Count CalculatorNeutrophil Ratio Calculator

Important Note: All the Calculators listed in this site are for educational purpose only and we do not guarentee the accuracy of results. Please do consult with other sources as well.