Calculate LDL from total cholesterol, HDL, and triglycerides. Choose units and method. See non-HDL and conversions. Export table and results. Final line summarizes result clearly.
Friedewald (mmol/L): LDL = TC − HDL − TG/2.2.
If Non‑HDL is provided: LDL ≈ Non‑HDL − TG/2.2 (VLDL estimate).
Unit conversions: cholesterol mg/dL ↔ mmol/L uses 38.67. Triglycerides mg/dL ↔ mmol/L uses 88.57.
Accuracy declines when triglycerides exceed about 4.5 mmol/L (≈ 400 mg/dL) or in dyslipidemias.
| TC | HDL | TG | Units | LDL (mmol/L) |
|---|---|---|---|---|
| 5.2 | 1.3 | 1.6 | mmol/L | 3.173 |
| 200 | 50 | 150 | mg/dL | 3.103 |
| 4.8 | 1.1 | 1.2 | mmol/L | 3.155 |
| Quantity | mmol/L → mg/dL | mg/dL → mmol/L |
|---|---|---|
| Cholesterol (TC/HDL/LDL) | × 38.67 | ÷ 38.67 |
| Triglycerides (TG) | × 88.57 | ÷ 88.57 |
| VLDL estimate | VLDL ≈ TG/2.2 (when TG in mmol/L) | |
| Band | LDL (mmol/L) | Notes |
|---|---|---|
| Optimal (general) | < 2.6 | Many guidelines prefer lower in high risk |
| Near optimal | 2.6 – 3.3 | Consider overall risk profile |
| Borderline high | 3.4 – 4.0 | Lifestyle plus clinician advice |
| High | 4.1 – 4.9 | Clinical management often indicated |
| Very high | ≥ 5.0 | Urgent clinical review typically needed |
| Input | Typical range (mmol/L) | Entry tips |
|---|---|---|
| Total Cholesterol (TC) | 3.0 – 7.0 | From lab report; select correct units |
| HDL | 0.8 – 2.5 | High HDL improves ratios |
| Triglycerides (TG) | 0.5 – 4.5 | Prefer fasting for estimate accuracy |
| Non‑HDL (optional) | 2.0 – 5.5 | Auto-computed if TC and HDL provided |
It uses Friedewald LDL = TC − HDL − TG/2.2 in mmol/L, with mg/dL conversions using 38.67 for cholesterol and 88.57 for triglycerides. Accuracy declines when triglycerides exceed about 4.5 mmol/L or in dyslipidemias.
Yes; select mg/dL in Units. The calculator converts internally to mmol/L, applies the formula, then shows LDL and non‑HDL in both units. The quick converter box helps convert single values fast.
Avoid with triglycerides above ~4.5 mmol/L, non‑fasting very high triglycerides, type III dyslipidemia, severe hypertriglyceridemia, pregnancy, or acute illness. Consider direct LDL measurement per your laboratory or clinician.
Non‑HDL equals Total Cholesterol minus HDL. It captures atherogenic lipoproteins, including LDL, VLDL, and remnants. It stays informative when triglycerides are high and is often a secondary treatment target.
VLDL cholesterol is approximated as TG/2.2 when triglycerides are in mmol/L. Remnant cholesterol equals Non‑HDL minus LDL. These are estimates and may differ from direct laboratory measurements.
Common targets include ≤3.0 mmol/L (low risk), ≤2.6 mmol/L (moderate), ≤1.8 mmol/L (high), and ≤1.4 mmol/L (very high). Follow local guidelines and personalized advice from your clinician.
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