Carboplatin AUC Dose Calculator

Calculate dose using direct filtration or clearance inputs. Compare single or repeated treatment scenarios quickly. Export results, inspect trends, and document planning with confidence.

Carboplatin AUC Dose Form

Target AUC

Renal Function Mode

Optional Clearance Cap (mL/min)

Round Dose To (mg)

Direct Kidney Function (mL/min)

Age (years)

Sex

Weight (kg)

Serum Creatinine (mg/dL)

Example Data Table

Case	Target AUC	Renal Function (mL/min)	Estimated Dose (mg)
Example 1	4	55	320
Example 2	5	60	425
Example 3	6	70	570
Example 4	5	80	525

Formula Used

The calculator uses the Calvert dosing structure:

Dose (mg) = Target AUC × (Renal Function + 25)

If you choose direct entry, the entered kidney function value is used in the formula. If you choose estimation mode, creatinine clearance is estimated with the Cockcroft-Gault equation, then the selected cap and rounding options are applied.

How to Use This Calculator

Enter the target AUC ordered for the treatment plan.
Select either direct kidney function entry or creatinine-based estimation.
If estimating, enter age, sex, weight, and serum creatinine.
Set an optional renal function cap and optional dose rounding rule.
Press calculate to show the dose, trend graph, and scenario table above the form.

Important Note

This page is for educational and planning support. Final treatment decisions should follow the treating oncology team's protocol, patient-specific assessment, local policy, and verified laboratory data.

FAQs

1. What does AUC mean here?

AUC means area under the concentration-time curve. In carboplatin dosing, it expresses the intended drug exposure rather than using only body surface area.

2. Which dose formula does this page use?

It uses the Calvert method: dose equals target AUC multiplied by renal function plus 25. The displayed result is shown in milligrams.

3. Can I enter a measured kidney function directly?

Yes. Choose direct entry when you already have the renal function value you want to use for dose planning.

4. Why is there an optional renal function cap?

Some services apply a local cap during planning. This field lets you model that workflow without forcing a cap for every case.

5. Is the creatinine-based estimate exact?

No. It is an estimate based on entered values. It helps with planning, but clinical review is still needed before treatment decisions.

6. Why does the calculator show a rounded dose?

Many teams review both the raw output and a rounded value. This helps compare the math result with a practical preparation target.

7. Does this replace oncology orders?

No. It supports checking and documenting calculations. Prescribing and verification remain clinical responsibilities.

8. What units should I enter?

Enter weight in kilograms, serum creatinine in mg/dL, renal function in mL/min, and the target exposure as the ordered AUC value.