Calculator
Formula Used
The calculator first converts progesterone into pg/mL when needed.
Progesterone pg/mL = Progesterone ng/mL × 1000
Then it divides converted progesterone by estradiol in pg/mL.
P:E2 Ratio = Progesterone pg/mL ÷ Estradiol pg/mL
For unit conversion, progesterone nmol/L is divided by 3.18. Estradiol pmol/L is divided by 3.671.
How to Use This Calculator
Enter your progesterone value from a lab report.
Select the matching progesterone unit.
Enter your estradiol value and select its unit.
Add cycle day and phase if you know them.
Press the calculate button.
The result appears above the form and below the header.
Use the export buttons to save your result.
Example Data Table
| Case | Progesterone | Estradiol | Converted Progesterone | Ratio | Phase |
|---|---|---|---|---|---|
| Example 1 | 12 ng/mL | 120 pg/mL | 12000 pg/mL | 100:1 | Luteal |
| Example 2 | 25.4 nmol/L | 550 pmol/L | 7987.42 pg/mL | 53.31:1 | Follicular |
| Example 3 | 18 ng/mL | 90 pg/mL | 18000 pg/mL | 200:1 | Luteal |
About Progesterone Estradiol Ratio
Why This Ratio Matters
The progesterone estradiol ratio compares two important hormones. Progesterone is often linked with the luteal phase. Estradiol is a major estrogen. Both hormones change across the menstrual cycle. Their values can also change with age, medication, pregnancy, and treatment. A ratio can help organize lab numbers. It should not replace medical judgment. Timing is very important. A luteal result means something different from a follicular result. That is why this calculator includes cycle day and phase.
Advanced Unit Handling
Lab reports do not always use the same units. Progesterone may appear as ng/mL or nmol/L. Estradiol may appear as pg/mL or pmol/L. This tool converts those units before calculating. It uses pg/mL as the shared comparison base. That gives a cleaner ratio. It also reduces manual conversion mistakes. Always copy values exactly from your report. Do not round too early. Small changes can affect the final number.
Understanding the Output
The result is shown as a simple P:E2 ratio. A higher value means progesterone is larger compared with estradiol. A lower value means estradiol is larger compared with progesterone. This does not prove a health problem. It only describes the relationship between two lab values. Symptoms, history, cycle phase, and test method matter. Saliva, serum, and urine testing may not compare equally. A clinician can review the full context.
Safe Use
Use this calculator for learning and record keeping. Save the CSV file for spreadsheets. Save the PDF file for sharing. Review results with licensed care professionals. Do not start or stop hormones from this result alone. Use careful notes. Good context makes hormone tracking more useful.
FAQs
1. What is the progesterone estradiol ratio?
It compares progesterone with estradiol after converting values into compatible units. It helps organize lab data but does not diagnose a condition.
2. Which units can I use?
You can enter progesterone as ng/mL or nmol/L. You can enter estradiol as pg/mL or pmol/L. The calculator converts them automatically.
3. Why is progesterone converted to pg/mL?
Estradiol is commonly reported in pg/mL. Converting progesterone to pg/mL creates a shared base before dividing the two values.
4. Is a high ratio always better?
No. A high ratio is not automatically better. Hormone meaning depends on cycle phase, symptoms, lab method, and medical history.
5. When should I test these hormones?
Testing time depends on the reason for testing. Many cycle reviews use luteal phase timing. Your clinician can advise the correct day.
6. Can this calculator diagnose estrogen dominance?
No. It can support discussion, but diagnosis needs clinical review. Symptoms, history, timing, and full lab panels should be considered.
7. Can I download my result?
Yes. After calculation, use the CSV button for spreadsheet data. Use the PDF button for a simple printable report.
8. Should I change medicine based on this result?
No. Do not change hormone treatment from this calculator alone. Discuss results with a licensed healthcare professional first.