Overview
A T2 iron liver calculator helps review MRI relaxometry numbers. It does not replace a radiology report. It turns T2 star or R2 star data into estimated liver iron concentration. The result is shown in milligrams of iron per gram of dry liver. This unit is often called mg Fe/g dry weight. The tool also shows micromoles per gram for teams that prefer that unit.
Why T2 Star Matters
Iron shortens the MRI signal decay time. A lower T2 star value usually means higher iron. R2 star is the inverse rate. It rises as iron rises. Because scanners, field strength, fitting methods, and regions of interest can change results, calibration choice matters. Always compare results from similar methods when tracking a patient.
Main Calculation Method
The calculator can use a linear Wood style equation. It can also use a T2 star power model. A custom linear option is included for local protocols. For 3 tesla studies, the page can estimate a 1.5 tesla equivalent R2 star before applying selected calibration. This is only a practical comparison aid. Your imaging center’s validated method should control final reporting.
Reading the Result
The final LIC estimate is grouped into normal, mild, moderate, severe, or very severe ranges. These ranges are guides only. They are not treatment orders. The uncertainty setting adds a simple lower and upper range. It helps show how small fitting errors can change the estimate.
Safe Use
Use measured liver values from a proper multi echo MRI sequence. Avoid vessels, bile ducts, artifacts, and edge pixels when drawing regions. Enter several regions when available. The average will be more stable than one small area. Keep the same scanner protocol for follow up whenever possible.
Practical Notes
Export the table after each calculation. The CSV works for spreadsheets. The PDF gives a compact record. Keep patient identifiers minimal when storing files. Discuss high or changing values with a qualified clinician. Treatment decisions depend on symptoms, diagnosis, ferritin trends, transfusion history, and the full MRI report. This calculator supports review. It should not direct care. When reports disagree, prefer the value from the interpreting radiologist. Local validation and consistent technique matter more than calculator convenience for long term monitoring.