Calculator Inputs
Example Data Table
Illustrative fasting examples only. These rows help users understand the input format and result pattern.
| Example | Fasting Glucose | Fasting Insulin | Converted Glucose | HOMA-IR | Observation |
|---|---|---|---|---|---|
| Case A | 88 mg/dL | 4.5 µIU/mL | 4.89 mmol/L | 0.98 | Lower relative signal using common study bands. |
| Case B | 96 mg/dL | 10.0 µIU/mL | 5.33 mmol/L | 2.37 | Near common adult screening bands in many studies. |
| Case C | 112 mg/dL | 18.0 µIU/mL | 6.22 mmol/L | 4.98 | Higher calculated score requiring clinical context. |
Formula Used
Primary equation
HOMA-IR = fasting insulin × fasting glucose (mmol/L) ÷ 22.5
Use this version when glucose is entered in mmol/L.
Equivalent equation
HOMA-IR = fasting insulin × fasting glucose (mg/dL) ÷ 405
This version is algebraically equivalent after glucose conversion.
The calculator converts glucose automatically, applies the correct equation, and then compares the output with your adjustable reference bands.
Because published cut points differ by age, ethnicity, weight status, study design, and laboratory method, the reference bands are configurable.
How to Use This Calculator
- Enter a fasting glucose value from a fasting blood sample.
- Choose the glucose unit, either mg/dL or mmol/L.
- Enter fasting insulin and keep the matching insulin unit selected.
- Set reference band 1 and reference band 2 for your preferred comparison ranges.
- Choose decimal precision and the graph span around your current input point.
- Press the calculate button to show the result above the form.
- Review the value, interpretation band, converted glucose units, and heatmap.
- Use the CSV or PDF buttons to export a compact summary report.
Frequently Asked Questions
1) What does HOMA-IR measure?
HOMA-IR is a fasting surrogate index built from glucose and insulin. It estimates how strongly the body may be resisting insulin, but it does not replace clinical diagnosis.
2) Which formula does this calculator use?
It uses insulin × glucose in mmol/L ÷ 22.5. When glucose is entered in mg/dL, the calculator applies the equivalent ÷ 405 form automatically.
3) Should glucose and insulin be fasting values?
Yes. HOMA-IR is designed for fasting measurements. A fasting sample is generally taken after at least 8 hours without caloric intake.
4) Are HOMA-IR cutoffs universal?
No. Published thresholds vary across populations, study methods, age groups, and laboratory assays. That is why this page lets you set your own comparison bands.
5) Can this tool diagnose diabetes?
No. It is an educational screening aid. Diagnosis requires clinical history, validated laboratory testing, and professional interpretation.
6) Why are there two glucose units?
Different labs report fasting glucose in different unit systems. The calculator supports both common formats and converts them automatically for consistency.
7) Why does the graph matter?
The graph shows how nearby changes in fasting glucose or insulin alter the final score. This helps users understand sensitivity around the entered point.
8) What do the export buttons save?
They export the current result summary, including inputs, converted values, HOMA-IR, interpretation band, and equation used for review or sharing.