Enter Clinical Inputs
The calculator stacks the form in one page flow, while the input grid changes to 3 columns on large screens, 2 on tablets, and 1 on mobile.
Example Data Table
| Case | Etiology | LSM kPa | Platelets | Albumin | Bilirubin | INR | Creatinine | Sodium | Expected Pattern |
|---|---|---|---|---|---|---|---|---|---|
| A | Viral | 13.8 | 178 | 3.9 | 1.1 | 1.2 | 0.9 | 138 | CSPH ruled out |
| B | Alcohol-related | 22.4 | 128 | 3.2 | 2.4 | 1.7 | 1.1 | 134 | Grey zone, higher probability |
| C | MASLD | 31.5 | 92 | 2.7 | 3.8 | 2.0 | 1.5 | 130 | High-risk / probable CSPH |
Formula Used
1) Baveno VII noninvasive portal hypertension logic
Rule out CSPH when liver stiffness is ≤ 15 kPa and platelets are ≥ 150 × 109/L.
Rule in CSPH when liver stiffness is ≥ 25 kPa, especially in viral, alcohol-related, and non-obese MASLD patterns.
Grey zone: 20–25 kPa with platelets < 150, or 15–20 kPa with platelets < 110, suggests higher probability.
2) Rule of five for stiffness severity
10, 15, 20, and 25 kPa define progressively higher risk tiers. Values 50–75 kPa indicate a critical stiffness range.
3) MELD-Na
MELD = 3.78 × ln(bilirubin) + 11.2 × ln(INR) + 9.57 × ln(creatinine) + 6.43
MELD-Na = MELD + 1.32 × (137 − sodium) − 0.033 × MELD × (137 − sodium)
4) Child-Pugh
Five domains are scored: bilirubin, albumin, INR, ascites, and encephalopathy. Total 5–6 = A, 7–9 = B, 10–15 = C.
5) Educational composite risk index
The final percentage blends Baveno VII category, MELD-Na, Child-Pugh, platelet depletion, spleen size, and decompensation markers. It is a transparent educational overlay, not a validated medical probability.
How to Use This Calculator
- Enter liver stiffness from transient elastography in kPa.
- Add platelet count and current liver reserve labs.
- Select ascites, encephalopathy, and any direct portal hypertension findings.
- Submit the form to generate the portal hypertension interpretation.
- Review the Baveno category, MELD-Na, Child-Pugh, and graph together.
- Download CSV or PDF if you want a shareable snapshot.
- Use the output as a discussion aid, not as a diagnosis.
FAQs
1) What does CSPH mean?
CSPH means clinically significant portal hypertension. It identifies a pressure-related stage linked with higher risk of decompensation, varices, and bleeding-related complications.
2) Is this calculator a diagnosis?
No. It is an educational estimator built from noninvasive thresholds and severity scores. Diagnosis still depends on specialist review, imaging, endoscopy, symptoms, and full context.
3) Why are platelets included?
Lower platelets often accompany splenic sequestration and advancing portal hypertension. They improve risk classification when paired with liver stiffness values.
4) Why do BMI and MASLD matter here?
In MASLD with obesity, very high stiffness can still mean increased risk, but rule-in precision may be lower. That is why the tool adds a caution note.
5) Can someone avoid endoscopy with low-risk results?
Some patients meeting low-risk stiffness and platelet criteria may avoid screening endoscopy, but the final decision belongs to the treating clinician.
6) Why show MELD-Na and Child-Pugh too?
Portal pressure risk and overall liver reserve are related but not identical. Showing both helps separate portal hypertension concern from overall hepatic function severity.
7) What is VITRO?
VITRO is the von Willebrand factor antigen to platelet ratio. It is an optional adjunct that can help interpret some unclassified cases.
8) When should urgent care be sought?
Vomiting blood, black stools, fainting, severe confusion, fever with abdominal swelling, or rapidly worsening jaundice need urgent medical evaluation immediately.